Chronic GVHD causes your immune system to become unbalanced. In people with chronic GVHD, the immune system overreacts, creating too many of some cells and not enough of others. This leads to inflammation (swelling) and fibrosis (scarring).
is swelling that occurs because your body is trying to protect itself.
Inflammation that goes on for a long time, like in chronic GVHD, may cause damage to your body.
is the growth of scar tissue that hardens and keeps your organs from working properly.
In some people, fibrosis happens when inflammation goes on for a long time. It is also possible for scar tissue to form without any inflammation.
Symptoms of chronic GVHD include
Painful skin rashes,
along with skin
thickening or tightening
Stiff joints and trouble
using your fingers,
hands, elbows, knees
Dry eyes or vision changes
Chronic cough, shortness of breath or difficulty breathing
Nausea, vomiting, diarrhea or loss of appetite
General decline in
health, including fatigue
Increased cases of depression or anxiety
Social interaction problems
Lack of energy
Reduced ability to
out daily tasks
If you’re on medicine but continue to have these symptoms, talk with your health care team. REZUROCK may be right for you.
GVHD, graft-versus-host disease.