Chronic GVHD causes your immune system to become unbalanced

During a blood stem cell transplant, stem cells from a donor (the graft) are added to your body (the host).

DONOR CELLS MAy

Attack

Your body’s cells and organs BECAUSE THEY SEE THEM As a threat.

When this happens, it can lead to chronic GVHD. Chronic GVHD causes your immune system to become unbalanced, creating too many of some cells and not enough of others. This leads to inflammation (swelling) and fibrosis (scarring), which can damage your organs.

illustration that shows how chronic graft-versus-host disease (chronic GVHD) may attack different parts of the body illustration that shows how chronic graft-versus-host disease (chronic GVHD) may attack different parts of the body

How is REZUROCK different?

Most medicines for chronic GVHD are immunosuppressants (ih-myoo-no-suh-preh-sents). These medicines suppress (reduce the strength of) your immune system. While these medicines can help treat your condition, they can also lower your body’s ability to fight something it recognizes as being an invader, such as an infection.

REZUROCK is different. It can help REBALANCE your immune system. REZUROCK is the only approved medicine that blocks the ROCK2 pathway in your body and may reduce the symptoms of inflammation and fibrosis.

Find out the difference REZUROCK can make.

Watch how REZUROCK works

GVHD, graft-versus-host disease.