People with chronic graft-versus-host disease (chronic GVHD)
struggle physically and emotionally. REZUROCK was shown to help

REZUROCK was evaluated in 2 clinical studies that included a total of 186 people.

More than

7OUT OF10

people in the ROCKstar study found symptom relief

Many people found symptom relief within 4 to 8 weeks.

Everyone responds to medicine differently. Some people may take longer to respond, especially if their organs are damaged by scarring.

People saw improvement across multiple organs

pink circular icon of an arm with a skin rash

Skin

pink circular icon of an eye

Eyes

pink circular icon of an open mouth with teeth

Mouth

pink circular icon of a bent knee joint

Joints and
muscles

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GI tract

pink circular icon of the liver

Liver

pink circular icon of the lungs

Lungs

pink circular icon of the esophagus

Esophagus

People saw improvement across multiple organs

pink circular icon of an arm with a skin rash

Skin

pink circular icon of an eye

Eyes

pink circular icon of the intestinal tract

GI tract

pink circular icon of the liver

Liver

pink circular icon of an open mouth with teeth

Mouth

pink circular icon of a bent knee joint

Joints and
muscles

pink circular icon of the lungs

Lungs

pink circular icon of the esophagus

Esophagus

In some people, REZUROCK also reduced the need
for steroids and other immunosuppressants.

People who found symptom relief with REZUROCK were at different stages of their treatment journey and

  • Tried different medicines, besides steroids, for chronic GVHD that failed to control their symptoms
  • Had either mild, moderate or severe chronic GVHD
  • Had 1 or more organs affected by chronic GVHD

Immunosuppressants (ih-myoo-no-suh-preh-sents), such as steroids, suppress (reduce the strength of) your immune system.

What are the side effects of REZUROCK?

Why most people were able to keep taking REZUROCK

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In clinical studies, side effects with REZUROCK were similar to those expected in people receiving steroids and other medicines for chronic GVHD.

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There were NO NEW CASES of cytomegalovirus (CMV) infection and only 1 case of recurring CMV infection.

CMV is a common serious infection that can happen in people who have had a blood stem cell transplant.

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There was a low rate of serious cytopenia (site-oh-pee-nia), a condition that causes a lower-than-normal number of certain blood cells.

The most common side effects reported by people taking REZUROCK in clinical studies were

  • Infections
  • Tiredness or weakness
  • Nausea
  • Diarrhea
  • Shortness of breath
  • Cough
  • Swelling
  • Bleeding
  • Stomach (abdominal) pain
  • Muscle or bone pain
  • Headache
  • High blood pressure

Be sure to tell your health care provider about any side effects you have. They may be able to help you find ways to manage them.

GI, gastrointestinal; GVHD, graft-versus-host disease.